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A Peroxiredoxin Promotes H(2)O(2) Signaling and Oxidative Stress Resistance by Oxidizing a Thioredoxin Family Protein

H(2)O(2) can cause oxidative damage associated with age-related diseases such as diabetes and cancer but is also used to initiate diverse responses, including increased antioxidant gene expression. Despite significant interest, H(2)O(2)-signaling mechanisms remain poorly understood. Here, we present...

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Detalles Bibliográficos
Autores principales: Brown, Jonathon D., Day, Alison M., Taylor, Sarah R., Tomalin, Lewis E., Morgan, Brian A., Veal, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898613/
https://www.ncbi.nlm.nih.gov/pubmed/24268782
http://dx.doi.org/10.1016/j.celrep.2013.10.036