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MicroRNA-26a is Strongly Down-regulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains (SODD)

Melanoma is an aggressive cancer that metastasizes rapidly, and is refractory to conventional chemotherapies. Identifying miRNAs that are responsible for this pathogenesis is therefore a promising means of developing new therapies. We identified miR-26a through microarray and qRT-PCR experiments as...

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Detalles Bibliográficos
Autores principales: Reuland, Steven N., Smith, Shilo, Bemis, Lynne, Goldstein, Nathaniel B., Almeida, Adam, Partyka, Katie A, Marquez, Victor E., Zhang, Qinghong, Norris, David A., Shellman, Yiqun G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898712/
https://www.ncbi.nlm.nih.gov/pubmed/23190898
http://dx.doi.org/10.1038/jid.2012.400