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Spindle Assembly Checkpoint of Oocytes Depends on a Kinetochore Structure Determined by Cohesin in Meiosis I

Since the dissolution of sister chromatid cohesion by separase and cyclin B destruction is irreversible, it is essential to delay both until all chromosomes have bioriented on the mitotic spindle. Kinetochores that are not correctly attached to the spindle generate the mitotic checkpoint complex (MC...

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Detalles Bibliográficos
Autores principales: Tachibana-Konwalski, Kikuë, Godwin, Jonathan, Borsos, Máté, Rattani, Ahmed, Adams, David J., Nasmyth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898714/
https://www.ncbi.nlm.nih.gov/pubmed/24291092
http://dx.doi.org/10.1016/j.cub.2013.10.052