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Dysregulation of microRNA expression drives aberrant DNA hypermethylation in basal-like breast cancer

Basal-like breast cancers frequently express aberrant DNA hypermethylation associated with concurrent silencing of specific genes secondary to DNMT3b overexpression and DNMT hyperactivity. DNMT3b is known to be post-transcriptionally regulated by microRNAs. The objective of the current study was to...

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Detalles Bibliográficos
Autores principales: SANDHU, RUPNINDER, RIVENBARK, ASHLEY G., MACKLER, RANDI M., LIVASY, CHAD A., COLEMAN, WILLIAM B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898722/
https://www.ncbi.nlm.nih.gov/pubmed/24297604
http://dx.doi.org/10.3892/ijo.2013.2197