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Dysregulation of microRNA expression drives aberrant DNA hypermethylation in basal-like breast cancer
Basal-like breast cancers frequently express aberrant DNA hypermethylation associated with concurrent silencing of specific genes secondary to DNMT3b overexpression and DNMT hyperactivity. DNMT3b is known to be post-transcriptionally regulated by microRNAs. The objective of the current study was to...
Autores principales: | SANDHU, RUPNINDER, RIVENBARK, ASHLEY G., MACKLER, RANDI M., LIVASY, CHAD A., COLEMAN, WILLIAM B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898722/ https://www.ncbi.nlm.nih.gov/pubmed/24297604 http://dx.doi.org/10.3892/ijo.2013.2197 |
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