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High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination
Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution Saccharomyces cerevisiae genome replication data with a mathematical model allows quantification of the stochastic nature of genome replication,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898788/ https://www.ncbi.nlm.nih.gov/pubmed/24210825 http://dx.doi.org/10.1016/j.celrep.2013.10.014 |