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A Novel Equation for Cooperativity of the Allosteric State Function()
The MWC (Monod–Wyman–Changeux) allosteric model postulates concerted conformational changes between two states: the intrinsically more stable T state with relatively weak ligand binding and the R state with relatively strong ligand binding. The model distinguishes between [Formula: see text] (the fr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898861/ https://www.ncbi.nlm.nih.gov/pubmed/24051418 http://dx.doi.org/10.1016/j.jmb.2013.09.010 |