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The BEG (PP2A-B55/ENSA/Greatwall) Pathway Ensures Cytokinesis follows Chromosome Separation

Cytokinesis follows separase activation and chromosome segregation. This order is ensured in budding yeast by the mitotic exit network (MEN), where Cdc14p dephosphorylates key conserved Cdk1-substrates exemplified by the anaphase spindle-elongation protein Ase1p. However, in metazoans, MEN and Cdc14...

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Detalles Bibliográficos
Autores principales: Cundell, Michael J., Bastos, Ricardo Nunes, Zhang, Tongli, Holder, James, Gruneberg, Ulrike, Novak, Bela, Barr, Francis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898901/
https://www.ncbi.nlm.nih.gov/pubmed/24120663
http://dx.doi.org/10.1016/j.molcel.2013.09.005