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Ectopic Recombination of a Malaria var Gene during Mitosis Associated with an Altered var Switch Rate

The Plasmodium falciparum var multigene family encodes P. falciparum erythrocyte membrane protein 1, which is responsible for the pathogenic traits of antigenic variation and adhesion of infected erythrocytes to host receptors during malaria infection. Clonal antigenic variation of P. falciparum ery...

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Detalles Bibliográficos
Autores principales: Duffy, Michael F., Byrne, Timothy J., Carret, Celine, Ivens, Alasdair, Brown, Graham V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898907/
https://www.ncbi.nlm.nih.gov/pubmed/19389407
http://dx.doi.org/10.1016/j.jmb.2009.04.032