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Randomised Pharmacokinetic Trial of Rifabutin with Lopinavir/Ritonavir-Antiretroviral Therapy in Patients with HIV-Associated Tuberculosis in Vietnam

BACKGROUND: Rifampicin and protease inhibitors are difficult to use concomitantly in patients with HIV-associated tuberculosis because of drug-drug interactions. Rifabutin has been proposed as an alternative rifamycin, but there is concern that the current recommended dose is suboptimal. The princip...

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Detalles Bibliográficos
Autores principales: Lan, Nguyen Thi Ngoc, Thu, Nguyen Thi Nguyet, Barrail-Tran, Aurélie, Duc, Nguyen Hong, Lan, Nguyen Ngoc, Laureillard, Didier, Thi Xuan Lien, Truong, Borand, Laurence, Quillet, Catherine, Connolly, Catherine, Lagarde, Dominique, Pym, Alexander, Lienhardt, Christian, Dung, Nguyen Huy, Taburet, Anne-Marie, Harries, Anthony D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898920/
https://www.ncbi.nlm.nih.gov/pubmed/24465443
http://dx.doi.org/10.1371/journal.pone.0084866