Novel R-roscovitine NO-donor hybrid compounds as potential pro-resolution of inflammation agents

Neutrophils play a pivotal role in the pathophysiology of multiple human inflammatory diseases. Novel pharmacological strategies which drive neutrophils to undergo programmed cell death (apoptosis) have been shown to facilitate the resolution of inflammation. Both the cyclin-dependent kinase inhibit...

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Detalles Bibliográficos
Autores principales: Montanaro, Gabriele, Bertinaria, Massimo, Rolando, Barbara, Fruttero, Roberta, Lucas, Christopher D., Dorward, David A., Rossi, Adriano G., Megson, Ian L., Gasco, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898921/
https://www.ncbi.nlm.nih.gov/pubmed/23394865
http://dx.doi.org/10.1016/j.bmc.2013.01.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898921/
https://www.ncbi.nlm.nih.gov/pubmed/23394865
http://dx.doi.org/10.1016/j.bmc.2013.01.009

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