Cargando…
Influence of Aggregation and Route of Injection on the Biodistribution of Mouse Serum Albumin
Protein aggregates are a major risk factor for immunogenicity. Until now most studies on aggregate-driven immunogenicity have focused on linking physicochemical features of the aggregates to the formation of anti-drug antibodies. Lacking is however, basic knowledge on the effect of aggregation on th...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898957/ https://www.ncbi.nlm.nih.gov/pubmed/24465523 http://dx.doi.org/10.1371/journal.pone.0085281 |