Exploring a potential palonosetron allosteric binding site in the 5-HT(3) receptor()

Palonosetron (Aloxi) is a potent second generation 5-HT(3) receptor antagonist whose mechanism of action is not yet fully understood. Palonosetron acts at the 5-HT(3) receptor binding site but recent computational studies indicated other possible sites of action in the extracellular domain. To test...

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Detalles Bibliográficos
Autores principales: Del Cadia, Marta, De Rienzo, Francesca, Weston, David A., Thompson, Andrew J., Menziani, Maria Cristina, Lummis, Sarah C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898987/
https://www.ncbi.nlm.nih.gov/pubmed/24128813
http://dx.doi.org/10.1016/j.bmc.2013.09.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898987/
https://www.ncbi.nlm.nih.gov/pubmed/24128813
http://dx.doi.org/10.1016/j.bmc.2013.09.028

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