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Myosin II ATPase Activity Mediates the Long-Term Potentiation-Induced Exodus of Stable F-Actin Bound by Drebrin A from Dendritic Spines

The neuronal actin-binding protein drebrin A forms a stable structure with F-actin in dendritic spines. NMDA receptor activation causes an exodus of F-actin bound by drebrin A (DA-actin) from dendritic spines, suggesting a pivotal role for DA-actin exodus in synaptic plasticity. We quantitatively as...

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Detalles Bibliográficos
Autores principales: Mizui, Toshiyuki, Sekino, Yuko, Yamazaki, Hiroyuki, Ishizuka, Yuta, Takahashi, Hideto, Kojima, Nobuhiko, Kojima, Masami, Shirao, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899004/
https://www.ncbi.nlm.nih.gov/pubmed/24465547
http://dx.doi.org/10.1371/journal.pone.0085367