Deubiquitinating Enzyme Specificity for Ubiquitin Chain Topology Profiled by Di-Ubiquitin Activity Probes

Posttranslational modification with ubiquitin (Ub) controls many cellular processes, and aberrant ubiquitination can contribute to cancer, immunopathology, and neurodegeneration. The versatility arises from the ability of Ub to form polymer chains with eight distinct linkages via lysine side chains...

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Detalles Bibliográficos
Autores principales: McGouran, Joanna F., Gaertner, Selina R., Altun, Mikael, Kramer, Holger B., Kessler, Benedikt M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899023/
https://www.ncbi.nlm.nih.gov/pubmed/24290882
http://dx.doi.org/10.1016/j.chembiol.2013.10.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899023/
https://www.ncbi.nlm.nih.gov/pubmed/24290882
http://dx.doi.org/10.1016/j.chembiol.2013.10.012

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