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Hovenia dulcis Thunb Extract and Its Ingredient Methyl Vanillate Activate Wnt/β-Catenin Pathway and Increase Bone Mass in Growing or Ovariectomized Mice

The Wnt/β-catenin pathway is a potential target for development of anabolic agents to treat osteoporosis because of its role in osteoblast differentiation and bone formation. However, there is no clinically available anti-osteoporosis drug that targets this Wnt/β-catenin pathway. In this study, we s...

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Detalles Bibliográficos
Autores principales: Cha, Pu-Hyeon, Shin, Wookjin, Zahoor, Muhammad, Kim, Hyun-Yi, Min, Do Sik, Choi, Kang-Yell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899039/
https://www.ncbi.nlm.nih.gov/pubmed/24465596
http://dx.doi.org/10.1371/journal.pone.0085546