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Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage()
Primary cilia are slender, microtubule based structures found in the majority of cell types with one cilium per cell. In articular cartilage, primary cilia are required for chondrocyte mechanotransduction and the development of healthy tissue. Loss of primary cilia in Col2aCre;ift88(fl/fl) transgeni...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899052/ https://www.ncbi.nlm.nih.gov/pubmed/24345381 http://dx.doi.org/10.1016/j.jbiomech.2013.11.040 |