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Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage()

Primary cilia are slender, microtubule based structures found in the majority of cell types with one cilium per cell. In articular cartilage, primary cilia are required for chondrocyte mechanotransduction and the development of healthy tissue. Loss of primary cilia in Col2aCre;ift88(fl/fl) transgeni...

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Detalles Bibliográficos
Autores principales: Irianto, Jerome, Ramaswamy, Girish, Serra, Rosa, Knight, Martin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899052/
https://www.ncbi.nlm.nih.gov/pubmed/24345381
http://dx.doi.org/10.1016/j.jbiomech.2013.11.040