The Productive Entry Pathway of HIV-1 in Macrophages Is Dependent on Endocytosis through Lipid Rafts Containing CD4

Macrophages constitute an important reservoir of HIV-1 infection, yet HIV-1 entry into these cells is poorly understood due to the difficulty in genetically manipulating primary macrophages. We developed an effective genetic approach to manipulate the sub-cellular distribution of CD4 in macrophages,...

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Detalles Bibliográficos
Autores principales: van Wilgenburg, Bonnie, Moore, Michael D., James, William S., Cowley, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899108/
https://www.ncbi.nlm.nih.gov/pubmed/24465876
http://dx.doi.org/10.1371/journal.pone.0086071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899108/
https://www.ncbi.nlm.nih.gov/pubmed/24465876
http://dx.doi.org/10.1371/journal.pone.0086071

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