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Arsenic Trioxide Induces Apoptosis in Human Platelets via C-Jun NH(2)-Terminal Kinase Activation

Arsenic trioxide (ATO), one of the oldest drugs in both Western and traditional Chinese medicine, has become an effective anticancer drug, especially in the treatment of acute promyelocytic leukemia (APL). However, thrombocytopenia occurred in most of ATO-treated patients with APL or other malignant...

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Detalles Bibliográficos
Autores principales: Wu, Yicun, Dai, Jin, Zhang, Weilin, Yan, Rong, Zhang, Yiwen, Ruan, Changgeng, Dai, Kesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899281/
https://www.ncbi.nlm.nih.gov/pubmed/24466103
http://dx.doi.org/10.1371/journal.pone.0086445