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Arsenic Trioxide Induces Apoptosis in Human Platelets via C-Jun NH(2)-Terminal Kinase Activation
Arsenic trioxide (ATO), one of the oldest drugs in both Western and traditional Chinese medicine, has become an effective anticancer drug, especially in the treatment of acute promyelocytic leukemia (APL). However, thrombocytopenia occurred in most of ATO-treated patients with APL or other malignant...
Autores principales: | Wu, Yicun, Dai, Jin, Zhang, Weilin, Yan, Rong, Zhang, Yiwen, Ruan, Changgeng, Dai, Kesheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899281/ https://www.ncbi.nlm.nih.gov/pubmed/24466103 http://dx.doi.org/10.1371/journal.pone.0086445 |
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