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The Use of High-Throughput DNA Sequencing in the Investigation of Antigenic Variation: Application to Neisseria Species

Antigenic variation occurs in a broad range of species. This process resembles gene conversion in that variant DNA is unidirectionally transferred from partial gene copies (or silent loci) into an expression locus. Previous studies of antigenic variation have involved the amplification and sequencin...

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Detalles Bibliográficos
Autores principales: Davies, John K., Harrison, Paul F., Lin, Ya-Hsun, Bartley, Stephanie, Khoo, Chen Ai, Seemann, Torsten, Ryan, Catherine S., Kahler, Charlene M., Hill, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899283/
https://www.ncbi.nlm.nih.gov/pubmed/24466206
http://dx.doi.org/10.1371/journal.pone.0086704