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The Use of High-Throughput DNA Sequencing in the Investigation of Antigenic Variation: Application to Neisseria Species
Antigenic variation occurs in a broad range of species. This process resembles gene conversion in that variant DNA is unidirectionally transferred from partial gene copies (or silent loci) into an expression locus. Previous studies of antigenic variation have involved the amplification and sequencin...
Autores principales: | Davies, John K., Harrison, Paul F., Lin, Ya-Hsun, Bartley, Stephanie, Khoo, Chen Ai, Seemann, Torsten, Ryan, Catherine S., Kahler, Charlene M., Hill, Stuart A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899283/ https://www.ncbi.nlm.nih.gov/pubmed/24466206 http://dx.doi.org/10.1371/journal.pone.0086704 |
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