Effects of Sulforaphane and 3,3′-Diindolylmethane on Genome-Wide Promoter Methylation in Normal Prostate Epithelial Cells and Prostate Cancer Cells

Epigenetic changes, including aberrant DNA methylation, result in altered gene expression and play an important role in carcinogenesis. Phytochemicals such as sulforaphane (SFN) and 3,3′-diindolylmethane (DIM) are promising chemopreventive agents for the treatment of prostate cancer. Both have been...

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Detalles Bibliográficos
Autores principales: Wong, Carmen P., Hsu, Anna, Buchanan, Alex, Palomera-Sanchez, Zoraya, Beaver, Laura M., Houseman, E. Andres, Williams, David E., Dashwood, Roderick H., Ho, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899342/
https://www.ncbi.nlm.nih.gov/pubmed/24466240
http://dx.doi.org/10.1371/journal.pone.0086787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899342/
https://www.ncbi.nlm.nih.gov/pubmed/24466240
http://dx.doi.org/10.1371/journal.pone.0086787

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