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Activation of p38/JNK Pathway Is Responsible for Embelin Induced Apoptosis in Lung Cancer Cells: Transitional Role of Reactive Oxygen Species

The natural product embelin has been demonstrated to possess a wide range of therapeutic properties, however, the mechanisms by which it exerts anticancer effects are not yet clear. By monitoring the molecular changes associated during early apoptotic phase, we have identified the crucial role of ox...

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Detalles Bibliográficos
Autores principales: Avisetti, Deepa R., Babu, K. Suresh, Kalivendi, Shasi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899364/
https://www.ncbi.nlm.nih.gov/pubmed/24466324
http://dx.doi.org/10.1371/journal.pone.0087050