Cargando…
Activation of p38/JNK Pathway Is Responsible for Embelin Induced Apoptosis in Lung Cancer Cells: Transitional Role of Reactive Oxygen Species
The natural product embelin has been demonstrated to possess a wide range of therapeutic properties, however, the mechanisms by which it exerts anticancer effects are not yet clear. By monitoring the molecular changes associated during early apoptotic phase, we have identified the crucial role of ox...
Autores principales: | Avisetti, Deepa R., Babu, K. Suresh, Kalivendi, Shasi V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899364/ https://www.ncbi.nlm.nih.gov/pubmed/24466324 http://dx.doi.org/10.1371/journal.pone.0087050 |
Ejemplares similares
-
Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
por: Pereira, Lorena, et al.
Publicado: (2013) -
Polyphyllin VI Induces Apoptosis and Autophagy via Reactive Oxygen Species Mediated JNK and P38 Activation in Glioma
por: Liu, Wei, et al.
Publicado: (2020) -
Rasfonin promotes autophagy and apoptosis via upregulation of reactive oxygen species (ROS)/JNK pathway
por: Wang, Weijun, et al.
Publicado: (2016) -
Glibenclamide induces apoptosis by activating reactive oxygen species dependent JNK pathway in hepatocellular carcinoma cells
por: Yan, Bin, et al.
Publicado: (2017) -
Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway
por: Zhang, Lei, et al.
Publicado: (2017)