Nrf1 and Nrf2 Transcription Factors Regulate Androgen Receptor Transactivation in Prostate Cancer Cells

Despite androgen deprivation therapy (ADT), persistent androgen receptor (AR) signaling enables outgrowth of castration resistant prostate cancer (CRPC). In prostate cancer (PCa) cells, ADT may enhance AR activity through induction of oxidative stress. Herein, we investigated the roles of Nrf1 and N...

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Detalles Bibliográficos
Autores principales: Schultz, Michelle A., Hagan, Sharika S., Datta, Amrita, Zhang, Yiguo, Freeman, Michael L., Sikka, Suresh C., Abdel-Mageed, Asim B., Mondal, Debasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899380/
https://www.ncbi.nlm.nih.gov/pubmed/24466341
http://dx.doi.org/10.1371/journal.pone.0087204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899380/
https://www.ncbi.nlm.nih.gov/pubmed/24466341
http://dx.doi.org/10.1371/journal.pone.0087204

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