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The Bone Resorption Inhibitors Odanacatib and Alendronate Affect Post-Osteoclastic Events Differently in Ovariectomized Rabbits

Odanacatib (ODN) is a bone resorption inhibitor which differs from standard antiresorptives by its ability to reduce bone resorption without decreasing bone formation. What is the reason for this difference? In contrast with other antiresorptives, such as alendronate (ALN), ODN targets only the very...

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Detalles Bibliográficos
Autores principales: Jensen, Pia Rosgaard, Andersen, Thomas Levin, Pennypacker, Brenda L., Duong, Le T., Delaissé, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899456/
https://www.ncbi.nlm.nih.gov/pubmed/24085265
http://dx.doi.org/10.1007/s00223-013-9800-0