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Clinical Pharmacokinetics of Clopidogrel and Its Metabolites in Patients with Cardiovascular Diseases

BACKGROUND AND OBJECTIVE: Approximately 5–40 % of patients treated with clopidogrel do not display an adequate antiplatelet response. Clopidogrel resistance may be caused by insufficient drug absorption or impaired metabolic activation of the drug. The aim of this study was to evaluate the pharmacok...

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Detalles Bibliográficos
Autores principales: Karaźniewicz-Łada, Marta, Danielak, Dorota, Burchardt, Paweł, Kruszyna, Łukasz, Komosa, Anna, Lesiak, Maciej, Główka, Franciszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899497/
https://www.ncbi.nlm.nih.gov/pubmed/24127209
http://dx.doi.org/10.1007/s40262-013-0105-2