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An Analysis of the Prognostic Value of IDH1 (Isocitrate Dehydrogenase 1) Mutation in Polish Glioma Patients

BACKGROUND AND OBJECTIVE: IDH1 (isocitrate dehydrogenase 1) is a potential biomarker and drug target. Genomic and epigenetic data on astrocytoma have demonstrated that the IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Furthermore, recent studies have also indicated t...

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Detalles Bibliográficos
Autores principales: Lewandowska, Marzena Anna, Furtak, Jacek, Szylberg, Tadeusz, Roszkowski, Krzysztof, Windorbska, Wiesława, Rytlewska, Joanna, Jóźwicki, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899509/
https://www.ncbi.nlm.nih.gov/pubmed/23934769
http://dx.doi.org/10.1007/s40291-013-0050-7