Cargando…

HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs

Hypoxia-inducible factor 1 (HIF-1) has been associated with distant tumor metastasis; however, its function in multiple metastatic processes has not yet been fully elucidated. In the present study, we demonstrated that cancer cells transiently upregulated HIF-1 activity during their metastatic colon...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Tao, Zhu, Yuxi, Morinibu, Akiyo, Kobayashi, Minoru, Shinomiya, Kazumi, Itasaka, Satoshi, Yoshimura, Michio, Guo, Guozheng, Hiraoka, Masahiro, Harada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899644/
https://www.ncbi.nlm.nih.gov/pubmed/24452734
http://dx.doi.org/10.1038/srep03793