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Divergent Label-free Cell Phenotypic Pharmacology of Ligands at the Overexpressed β(2)-Adrenergic Receptors

We present subclone sensitive cell phenotypic pharmacology of ligands at the β(2)-adrenergic receptor (β(2)-AR) stably expressed in HEK-293 cells. The parental cell line was transfected with green fluorescent protein (GFP)-tagged β(2)-AR. Four stable subclones were established and used to profile a...

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Detalles Bibliográficos
Autores principales: Ferrie, Ann M., Sun, Haiyan, Zaytseva, Natalya, Fang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899747/
https://www.ncbi.nlm.nih.gov/pubmed/24451999
http://dx.doi.org/10.1038/srep03828