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Role of EIF5A2, a downstream target of Akt, in promoting melanoma cell invasion

BACKGROUND: Cutaneous melanoma is a life-threatening skin cancer because of its poorly understood invasive nature and high metastatic potential. This study examines the importance of eukaryotic translation initiation factor 5A2 (EIF5A2) in melanoma pathogenesis. METHODS: We examined EIF5A2 expressio...

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Detalles Bibliográficos
Autores principales: Khosravi, S, Wong, R P C, Ardekani, G S, Zhang, G, Martinka, M, Ong, C J, Li, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899752/
https://www.ncbi.nlm.nih.gov/pubmed/24178756
http://dx.doi.org/10.1038/bjc.2013.688