Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour–stroma interaction

BACKGROUND: Interleukin-6 (IL-6) has an important role in cancer progression, and high levels of plasma IL-6 are correlated with a poor prognosis in a variety of cancers. It has also been reported that tumour stromal fibroblasts are necessary for steps in cancer progression, such as angiogenesis. Th...

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Detalles Bibliográficos
Autores principales: Nagasaki, T, Hara, M, Nakanishi, H, Takahashi, H, Sato, M, Takeyama, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899773/
https://www.ncbi.nlm.nih.gov/pubmed/24346288
http://dx.doi.org/10.1038/bjc.2013.748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899773/
https://www.ncbi.nlm.nih.gov/pubmed/24346288
http://dx.doi.org/10.1038/bjc.2013.748

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