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Trapping DNA Replication Origins from the Human Genome

Synthesis of chromosomal DNA is initiated from multiple origins of replication in higher eukaryotes; however, little is known about these origins’ structures. We isolated the origin-derived nascent DNAs from a human repair-deficient cell line by blocking the replication forks near the origins using...

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Detalles Bibliográficos
Autores principales: Eki, Toshihiko, Murakami, Yasufumi, Hanaoka, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899975/
https://www.ncbi.nlm.nih.gov/pubmed/24705160
http://dx.doi.org/10.3390/genes4020198