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DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking

Disrupted-In-Schizophrenia 1 (DISC1) is a candidate risk factor for schizophrenia, bipolar disorder and severe recurrent depression. Here, we demonstrate that DISC1 associates robustly with trafficking-protein-Kinesin-binding-1 which is, in turn, known to interact with the outer mitochondrial membra...

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Detalles Bibliográficos
Autores principales: Ogawa, Fumiaki, Malavasi, Elise L.V., Crummie, Darragh K., Eykelenboom, Jennifer E., Soares, Dinesh C., Mackie, Shaun, Porteous, David J., Millar, J. Kirsty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900104/
https://www.ncbi.nlm.nih.gov/pubmed/24092329
http://dx.doi.org/10.1093/hmg/ddt485