Selective ROCK2 inhibition in focal cerebral ischemia

OBJECTIVE: Rho-associated kinase (ROCK) is a key regulator of numerous processes in multiple cell types relevant in stroke pathophysiology. ROCK inhibitors have improved outcome in experimental models of acute ischemic or hemorrhagic stroke. However, the relevant ROCK isoform (ROCK1 or ROCK2) in acu...

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Detalles Bibliográficos
Autores principales: Hyun Lee, Jeong, Zheng, Yi, von Bornstadt, Daniel, Wei, Ying, Balcioglu, Aygul, Daneshmand, Ali, Yalcin, Nilufer, Yu, Esther, Herisson, Fanny, Atalay, Yahya B, Kim, Maya H, Ahn, Yong-Joo, Balkaya, Mustafa, Sweetnam, Paul, Schueller, Olivier, Poyurovsky, Masha V, Kim, Hyung-Hwan, Lo, Eng H, Furie, Karen L, Ayata, Cenk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900310/
https://www.ncbi.nlm.nih.gov/pubmed/24466563
http://dx.doi.org/10.1002/acn3.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900310/
https://www.ncbi.nlm.nih.gov/pubmed/24466563
http://dx.doi.org/10.1002/acn3.19

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