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Combinatorial Modeling of Chromatin Features Quantitatively Predicts DNA Replication Timing in Drosophila

In metazoans, each cell type follows a characteristic, spatio-temporally regulated DNA replication program. Histone modifications (HMs) and chromatin binding proteins (CBPs) are fundamental for a faithful progression and completion of this process. However, no individual HM is strictly indispensable...

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Detalles Bibliográficos
Autores principales: Comoglio, Federico, Paro, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900380/
https://www.ncbi.nlm.nih.gov/pubmed/24465194
http://dx.doi.org/10.1371/journal.pcbi.1003419