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Combinatorial Modeling of Chromatin Features Quantitatively Predicts DNA Replication Timing in Drosophila
In metazoans, each cell type follows a characteristic, spatio-temporally regulated DNA replication program. Histone modifications (HMs) and chromatin binding proteins (CBPs) are fundamental for a faithful progression and completion of this process. However, no individual HM is strictly indispensable...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900380/ https://www.ncbi.nlm.nih.gov/pubmed/24465194 http://dx.doi.org/10.1371/journal.pcbi.1003419 |