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Loss and Recovery of Genetic Diversity in Adapting Populations of HIV

The evolution of drug resistance in HIV occurs by the fixation of specific, well-known, drug-resistance mutations, but the underlying population genetic processes are not well understood. By analyzing within-patient longitudinal sequence data, we make four observations that shed a light on the under...

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Detalles Bibliográficos
Autores principales: Pennings, Pleuni S., Kryazhimskiy, Sergey, Wakeley, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900388/
https://www.ncbi.nlm.nih.gov/pubmed/24465214
http://dx.doi.org/10.1371/journal.pgen.1004000