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Loss and Recovery of Genetic Diversity in Adapting Populations of HIV
The evolution of drug resistance in HIV occurs by the fixation of specific, well-known, drug-resistance mutations, but the underlying population genetic processes are not well understood. By analyzing within-patient longitudinal sequence data, we make four observations that shed a light on the under...
Autores principales: | Pennings, Pleuni S., Kryazhimskiy, Sergey, Wakeley, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900388/ https://www.ncbi.nlm.nih.gov/pubmed/24465214 http://dx.doi.org/10.1371/journal.pgen.1004000 |
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