Down-Regulation of Rad51 Activity during Meiosis in Yeast Prevents Competition with Dmc1 for Repair of Double-Strand Breaks

Interhomolog recombination plays a critical role in promoting proper meiotic chromosome segregation but a mechanistic understanding of this process is far from complete. In vegetative cells, Rad51 is a highly conserved recombinase that exhibits a preference for repairing double strand breaks (DSBs)...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Gaines, William A., Callender, Tracy, Busygina, Valeria, Oke, Ashwini, Sung, Patrick, Fung, Jennifer C., Hollingsworth, Nancy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900393/
https://www.ncbi.nlm.nih.gov/pubmed/24465215
http://dx.doi.org/10.1371/journal.pgen.1004005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900393/
https://www.ncbi.nlm.nih.gov/pubmed/24465215
http://dx.doi.org/10.1371/journal.pgen.1004005

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