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Angiotensin-Induced Abdominal Aortic Aneurysms in Hypercholesterolemic Mice: Role of Serum Cholesterol and Temporal Effects of Exposure

OBJECTIVE: Understanding variations in size and pattern of development of angiotensin II (Ang II)-induced abdominal aortic aneurysms (AAA) may inform translational research strategies. Thus, we sought insight into the temporal evolution of AAA in apolipoprotein (apo)E(−/−) mice. APPROACH: A cohort o...

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Detalles Bibliográficos
Autores principales: Prins, Petra A., Hill, Michael F., Airey, David, Nwosu, Sam, Perati, Prudhvidhar R., Tavori, Hagai, F. Linton, MacRae, Kon, Valentina, Fazio, Sergio, Sampson, Uchechukwu K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900396/
https://www.ncbi.nlm.nih.gov/pubmed/24465413
http://dx.doi.org/10.1371/journal.pone.0084517