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BDNF Polymorphisms Are Linked to Poorer Working Memory Performance, Reduced Cerebellar and Hippocampal Volumes and Differences in Prefrontal Cortex in a Swedish Elderly Population

BACKGROUND: Brain-derived neurotrophic factor (BDNF) links learning, memory and cognitive decline in elderly, but evidence linking BDNF allele variation, cognition and brain structural differences is lacking. METHODS: 367 elderly Swedish men (n = 181) and women (n = 186) from Prospective Investigati...

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Detalles Bibliográficos
Autores principales: Brooks, Samantha J., Nilsson, Emil K., Jacobsson, Josefin A., Stein, Dan J., Fredriksson, Robert, Lind, Lars, Schiöth, Helgi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900399/
https://www.ncbi.nlm.nih.gov/pubmed/24465375
http://dx.doi.org/10.1371/journal.pone.0082707