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BDNF Polymorphisms Are Linked to Poorer Working Memory Performance, Reduced Cerebellar and Hippocampal Volumes and Differences in Prefrontal Cortex in a Swedish Elderly Population
BACKGROUND: Brain-derived neurotrophic factor (BDNF) links learning, memory and cognitive decline in elderly, but evidence linking BDNF allele variation, cognition and brain structural differences is lacking. METHODS: 367 elderly Swedish men (n = 181) and women (n = 186) from Prospective Investigati...
Autores principales: | Brooks, Samantha J., Nilsson, Emil K., Jacobsson, Josefin A., Stein, Dan J., Fredriksson, Robert, Lind, Lars, Schiöth, Helgi B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900399/ https://www.ncbi.nlm.nih.gov/pubmed/24465375 http://dx.doi.org/10.1371/journal.pone.0082707 |
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