Inverse Agonism of SQ 29,548 and Ramatroban on Thromboxane A2 Receptor

G protein-coupled receptors (GPCRs) show some level of basal activity even in the absence of an agonist, a phenomenon referred to as constitutive activity. Such constitutive activity in GPCRs is known to have important pathophysiological roles in human disease. The thromboxane A2 receptor (TP) is a...

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Detalles Bibliográficos
Autores principales: Chakraborty, Raja, Bhullar, Rajinder P., Dakshinamurti, Shyamala, Hwa, John, Chelikani, Prashen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900440/
https://www.ncbi.nlm.nih.gov/pubmed/24465800
http://dx.doi.org/10.1371/journal.pone.0085937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900440/
https://www.ncbi.nlm.nih.gov/pubmed/24465800
http://dx.doi.org/10.1371/journal.pone.0085937

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