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Inverse Agonism of SQ 29,548 and Ramatroban on Thromboxane A2 Receptor
G protein-coupled receptors (GPCRs) show some level of basal activity even in the absence of an agonist, a phenomenon referred to as constitutive activity. Such constitutive activity in GPCRs is known to have important pathophysiological roles in human disease. The thromboxane A2 receptor (TP) is a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900440/ https://www.ncbi.nlm.nih.gov/pubmed/24465800 http://dx.doi.org/10.1371/journal.pone.0085937 |