Two-Step Synthesis and Hydrolysis of Cyclic di-AMP in Mycobacterium tuberculosis

Cyclic di-AMP is a recently discovered signaling molecule which regulates various aspects of bacterial physiology and virulence. Here we report the characterization of c-di-AMP synthesizing and hydrolyzing proteins from Mycobacterium tuberculosis. Recombinant Rv3586 (MtbDisA) can synthesize c-di-AMP...

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Detalles Bibliográficos
Autores principales: Manikandan, Kasi, Sabareesh, Varatharajan, Singh, Nirpendra, Saigal, Kashyap, Mechold, Undine, Sinha, Krishna Murari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900455/
https://www.ncbi.nlm.nih.gov/pubmed/24465894
http://dx.doi.org/10.1371/journal.pone.0086096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900455/
https://www.ncbi.nlm.nih.gov/pubmed/24465894
http://dx.doi.org/10.1371/journal.pone.0086096

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