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Two-Step Synthesis and Hydrolysis of Cyclic di-AMP in Mycobacterium tuberculosis

Cyclic di-AMP is a recently discovered signaling molecule which regulates various aspects of bacterial physiology and virulence. Here we report the characterization of c-di-AMP synthesizing and hydrolyzing proteins from Mycobacterium tuberculosis. Recombinant Rv3586 (MtbDisA) can synthesize c-di-AMP...

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Detalles Bibliográficos
Autores principales:	Manikandan, Kasi, Sabareesh, Varatharajan, Singh, Nirpendra, Saigal, Kashyap, Mechold, Undine, Sinha, Krishna Murari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900455/ https://www.ncbi.nlm.nih.gov/pubmed/24465894 http://dx.doi.org/10.1371/journal.pone.0086096

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