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The feline bile salt export pump: a structural and functional comparison with canine and human Bsep/BSEP
BACKGROUND: The bile salt export pump (BSEP/ABCB11) is the primary transporter for the excretion of bile acids from hepatocytes into bile. In human, inhibition of BSEP by drugs has been related to drug-induced cholestasis and subsequent cytotoxic effects. The role of BSEP in canine and feline liver...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900472/ https://www.ncbi.nlm.nih.gov/pubmed/24359682 http://dx.doi.org/10.1186/1746-6148-9-259 |