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The feline bile salt export pump: a structural and functional comparison with canine and human Bsep/BSEP

BACKGROUND: The bile salt export pump (BSEP/ABCB11) is the primary transporter for the excretion of bile acids from hepatocytes into bile. In human, inhibition of BSEP by drugs has been related to drug-induced cholestasis and subsequent cytotoxic effects. The role of BSEP in canine and feline liver...

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Detalles Bibliográficos
Autores principales:	van Beusekom, Cyrina D, van den Heuvel, Jeroen JMW, Koenderink, Jan B, Schrickx, Johannes A, Russel, Frans GM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900472/ https://www.ncbi.nlm.nih.gov/pubmed/24359682 http://dx.doi.org/10.1186/1746-6148-9-259

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